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Anti-PRDM16 Polyclonal Antibody
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Catalog No. TMAB-01571
Alias Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL
Anti-PRDM16 Polyclonal Antibody is a Rabbit antibody targeting PRDM16. Anti-PRDM16 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Anti-PRDM16 Polyclonal Antibody
Anti-PRDM16 Polyclonal Antibody
😃Good
Catalog No. TMAB-01571Alias Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL
Anti-PRDM16 Polyclonal Antibody is a Rabbit antibody targeting PRDM16. Anti-PRDM16 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PRDM16 Polyclonal Antibody is a Rabbit antibody targeting PRDM16. Anti-PRDM16 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,ELISA. |
| Synonyms | Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in uterus and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human PRDM16 |
| Antigen Species | Human |
| Gene Name | PRDM16 |
| Gene ID | |
| Protein Name | Histone-lysine N-methyltransferase PRDM16 |
| Uniprot ID | |
| Biology Area | Methylation,Zinc Finger |
| Function | Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation. |
| Molecular Weight | Theoretical: 140 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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