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DIPQUO hydrochloride

Name: DIPQUO hydrochloride
Brand: TargetMol
SKU: T11048L
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11048L

Alias DIPQUO hydrochloride(1269365-82-3 Free base)

DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.

DIPQUO hydrochloride

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Purity: 98.09%

Catalog No. T11048LAlias DIPQUO hydrochloride(1269365-82-3 Free base)

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$45	In Stock	In Stock
5 mg	$79	In Stock	In Stock
10 mg	$133	In Stock	In Stock
25 mg	$209	In Stock	In Stock
50 mg	$291	In Stock	In Stock
100 mg	$400	In Stock	In Stock
200 mg	$541	-	In Stock
1 mL x 10 mM (in DMSO)	$89	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.09%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β.
In vitro	ALP activity was measured using a fluorescent emission assay as a reporter for enzymatic digestion of ALP substrate in lysates derived from C2C12 myoblasts, DIPQUO shows EC50 of 6.27 μM[1].
Synonyms	DIPQUO hydrochloride(1269365-82-3 Free base)

Chemical Properties

Molecular Weight	351.83
Formula	C₂₀H₁₈ClN₃O
Smiles	O=C1NC2=C(C=C1C3=C(C4=CC=CC=C4)N=CN3)C=C(C)C=C2C.Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (142.11 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8423 mL	14.2114 mL	28.4228 mL	142.1141 mL
5 mM	0.5685 mL	2.8423 mL	5.6846 mL	28.4228 mL
10 mM	0.2842 mL	1.4211 mL	2.8423 mL	14.2114 mL
20 mM	0.1421 mL	0.7106 mL	1.4211 mL	7.1057 mL
50 mM	0.0568 mL	0.2842 mL	0.5685 mL	2.8423 mL
100 mM	0.0284 mL	0.1421 mL	0.2842 mL	1.4211 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc