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CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated
(Synonyms: MXRA4, ECSM3, dJ737E23.1, CDw93, CD93, C1qRp, C1QR1, C1qR(p), C1qR, C1q/MBL/SPA receptor) Copy Product InfoSynonyms: MXRA4, ECSM3, dJ737E23.1, CDw93, CD93, C1qRp, C1QR1, C1qR(p), C1qR, C1q/MBL/SPA receptor
Catalog No. TMPK-01202 Copy Product Info
CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $91 | 7-10 days | 7-10 days | |
| 10 μg | $148 | 7-10 days | 7-10 days | |
| 20 μg | $245 | 7-10 days | 7-10 days | |
| 50 μg | $483 | 7-10 days | 7-10 days | |
| 100 μg | $813 | 7-10 days | 7-10 days | |
| 200 μg | $1,470 | 7-10 days | 7-10 days | |
| 500 μg | $3,250 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Immobilized Biotinylated Human CD93, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Human IGFBP7, hFc Tag with the EC50 of 27.9ng/ml determined by ELISA.
2. Biotinylated Human CD93, His-Avi Tag immobilized on CM5 Chip can bind Human IGFBP-7, His Tag with an affinity constant of 0.17 μM as determined in SPR assay. |
| Description | CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | Q9NPY3 |
| Construction | Thr22-Lys580 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | MXRA4, ECSM3, dJ737E23.1, CDw93, CD93, C1qRp, C1QR1, C1qR(p), C1qR, C1q/MBL/SPA receptor |
| Research Background |
| Molecular Weight | 61.2 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated chemical structure | CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated molecular weight
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