Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

IL Receptor

Interleukin receptors are a family of cytokine receptors for interleukins. They belong to the immunoglobulin superfamily.There are two main families of Interleukin receptors, Type 1 and Type 2.

Resiniferatoxin
T3429557444-62-9
Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist that inhibits the production of Th1 cytokines and has anti-inflammatory activity, reducing serum levels of IL-12, INF-γ, IL-1β, TNF-α, NO, and PGE.
  • $456
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Dupilumab
T136661190264-60-8
Dupilumab (REGN-668) is a fully human monoclonal antibody targeting the alpha subunit of the interleukin-4 receptor, thereby inhibiting IL-4 and IL-13 signaling. As a systemic immunomodulator, it has demonstrated efficacy in improving atopic dermatitis.
  • $239
In Stock
Size
QTY
TargetMol | Inhibitor Hot
5-O-Caffeoylshikimic acid
TN129573263-62-4
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
  • $98
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Olamkicept
T732091702282-14-1
Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that selectively inhibits interleukin 6 (IL-6) trans-signaling by binding to the soluble IL-6 receptor IL-6 complex.
  • $195
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Dexamethasone
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Hot
Secukinumab
T99301229022-83-6
Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the treatment of moderate to severe plaque psoriasis.
  • $147
In Stock
Size
QTY
Siltuximab
T76978541502-14-1
Siltuximab(CNTO-328) is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.
  • $178
In Stock
Size
QTY
Anakinra
T10317143090-92-0
Anakinra (Raleukin) is a cytokine inactivator and interleukin 1 receptor antagonist that can be used to study secondary phagocytic lymphohistiocytosis and rheumatoid arthritis.
  • $670
In Stock
Size
QTY
Apilimod
T2018541550-19-0
Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
  • $43
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Guselkumab
T383621350289-85-8
Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol L, respectively. Guselkumab can inhibit the production of cytokines downstream of IL-23 signaling pathway, and can be used in the study of psoriatic arthritis.
  • $579
In Stock
Size
QTY
Y-320
T1846288250-47-5
Y-320 is a new phenylpyrazoleanilide immunomodulator.
  • $39
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Spesolimab
T768842097104-58-8
Spesolimab (BI 655130) is an anti-interleukin-36 receptor antibody. It plays a crucial role in the immune system by reducing biomarkers associated with congenital Th1 Th17 and neutrophil pathways. Spesolimab can be used to study systemic pustular psoriasis, palmar and plantar impetigo (PPP), and atopic dermatitis.
  • $283
In Stock
Size
QTY
Ac-YVAD-CMK
T36347178603-78-6
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
  • $64
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Canakinumab
T73695914613-48-2
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.
  • $179
In Stock
Size
QTY
L-Arginine
T3S036474-79-3
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway. 4. A combination of oral L-citrulline and L-Arginine effectively and rapidly augments NO-dependent responses at the acute stage.
  • $31
In Stock
Size
QTY
Nothofagin
TN199611023-94-2In house
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
  • $293
In Stock
Size
QTY
Benralizumab
T104971044511-01-4
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, leading to a rapid depletion of eosinophils. Benralizumab is used for severe eosinophilic asthma and can be employed to prevent exacerbations of chronic obstructive pulmonary disease.
  • $538
In Stock
Size
QTY
Ixekizumab
T381051143503-69-8
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM. It blocks the binding of IL-17A to IL-17RA but not to other IL-17 family members. Ixekizumab is used for the treatment of moderate to severe plaque psoriasis, psoriasis, arthritis, and psoriasis.
  • $136
In Stock
Size
QTY
Berberrubine chloride
T4S079515401-69-1
1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
  • $30
In Stock
Size
QTY
Brodalumab
T767791174395-19-7
Brodalumab (AMG 827) is a human monoclonal IgG2 antibody targeting the interleukin 17 receptor (IL-17R), commonly used as an immunosuppressant in treating psoriasis.
  • $155
In Stock
Size
QTY
Moringin
TN458373255-40-0
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.
  • $138
In Stock
Size
QTY
TargetMol | Inhibitor Sale
AF 12198 Acetate
T21644L
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
  • $697
In Stock
Size
QTY
BIRT-377
T23796213211-10-0
BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.
  • $50
In Stock
Size
QTY
Aucubin
T3416479-98-1
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.
  • $33
In Stock
Size
QTY