Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | Inquiry | $ 489.00 | |
1 mg | Inquiry | $ 3,265.00 |
Description | Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa. |
Species | Human |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | AAA59600.1(HLA-A*24:02)&P61769(B2M)&IMPKAGLLI |
Synonyms | MAGE-3, CT1.3, Melanoma-associated antigen 3, MZ2D, MZ2-D, HLA-A*24:02, HLA-A2402 |
Construction | Recombinant Human HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M)and IMPKAGLLI peptide.[Accession |AAA59600.1(HLA-A*24:02)&P61769(B2M)&IMPKAGLLI] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt.-20 to -80°C for 3-6 months in unopened state after reconstitution.4-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa. |
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Please read the User Guide of Recombinant Proteins for more specific information.
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Tetramer Protein, Human, MHC (His & Avi) MAGE-3 CT1.3 Melanoma-associated antigen 3 MZ2D MZ2-D HLA-A*24:02 HLA-A2402 recombinant recombinant-proteins proteins protein