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Anti-CYCS Antibody (7Q735)

(Synonyms: Cytochrome C, CYCS, CYC) Copy Product Info
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Synonyms: Cytochrome C, CYCS, CYC

Catalog No. TMAB-00515 Copy Product Info
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Anti-CYCS Antibody (7Q735) is a Mouse antibody targeting CYCS. Anti-CYCS Antibody (7Q735) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-CYCS Antibody
(7Q735)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CYCS Antibody (7Q735) is a Mouse antibody targeting CYCS. Anti-CYCS Antibody (7Q735) can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB.
SynonymsCytochrome C, CYCS, CYC
Ig Type
IgG
Clone
7Q735
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
ICC/IF=1:100-500; IF=1:200-800; IHC-Fr=1:200-800; IHC-P=1:200-800; WB=1:2000-20000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundCytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome C has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome C is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
Antigen Details
Immunogen
Recombinant Protein: human Cytochrome C Protein
Antigen Species
Human
Gene Name
CYCS
Gene ID
Protein Name
Cytochrome c
Uniprot ID
Biology Area
Integration of energy metabolism,Cytochrome C,Metabolism,Mitochondrial,Cytochrome C,Cytochromes,Mitochondrial,Energy Metabolism,Integration of energy,Lipases,Apoptosis,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Energy Metabolism,Mitochondrial
Function
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Chemical Properties
Molecular WeightTheoretical: 12 kDa. Actual: 14 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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