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Anti-PBP Antibody (4X935) is a Rabbit antibody targeting PBP. Anti-PBP Antibody (4X935) can be used in WB,ICC/IF,IHC,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $497 | 7-10 days |
Description | Anti-PBP Antibody (4X935) is a Rabbit antibody targeting PBP. Anti-PBP Antibody (4X935) can be used in WB,ICC/IF,IHC,IP. |
Synonyms | RKIP, Raf kinase inhibitory protein, Raf kinase inhibitor protein, R kip, Prostatic-binding protein, Prostatic binding protein, Phosphatidylethanolamine binding protein 1, Phosphatidylethanolamine binding protein, PEBP1_HUMAN, PEBP-1, Pebp1, PEBP 1, PEBP, PBP, Neuropolypeptide h3, Hippocampal cholinergic neurostimulating peptide, HEL S 96, HEL S 34, HEL 210, HCNPpp, HCNP, Epididymis secretory protein Li 96, Epididymis secretory protein Li 34, Epididymis luminal protein 210 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat,zebrafish |
Verified Activity | 1. Western blot analysis of PBP on mouse brain lysates using anti-PBP antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-PBP antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PBP antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-PBP antibody. Counter stained with hematoxylin. 5. ICC staining PBP in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils. The platelet basic protein (PBP), a member of the a(lpha)-chemokine family, resides in the a(lpha)-granules of platelets and is released upon their activation. Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2). PBP and its N-truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The gene encoding human PBP maps to chromosome 4q12-q13. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 21 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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