FGF-7/KGF Protein, Mouse, Recombinant

Name: FGF-7/KGF Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00172
Rating: 4.5 (1 reviews)

(Synonyms: Keratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7) Copy Product Info

Synonyms: Keratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7

Catalog No. TMPS-00172 Copy Product Info

FGF-7/KGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P36363.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$170	7-10 days	7-10 days
20 µg	$228	7-10 days	7-10 days
50 µg	$339	7-10 days	7-10 days
100 µg	$618	7-10 days	7-10 days
200 µg	$1,130	7-10 days	7-10 days
500 µg	$2,560	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 2.0 ng/ml, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0 × 10 5 units/mg.
Description	FGF-7/KGF Protein, Mouse, Recombinant is expressed in E. coli. The accession number is P36363.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	P36363
Construction	Cys32-Thr194
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in PBS up to 100 μg/ml.
Synonyms	Keratinocyte Growth Factor, HBGF-7, Fibroblast Growth Factor-7, FGF7
Research Background	Keratinocyte Growth Factor (KGF) is a highly specific epithelial mitogen produced by fibroblasts and mesenchymal stem cells. KGF belongs to the heparin binding Fibroblast Growth Factor (FGF) family, and is known as FGF-7. However, in contrast to FGF-1, which binds to all known FGF receptors with high affinity, KGF only binds to a splice variant of the FGF receptor, FGFR2-IIIb. FGFR2-IIIb is expressedby most epithelial cells, indicating KGF’s roleas a paracrine mediator. KGF induces the differentiation and proliferation of various epithelial cells such as keratinocytes in the epidermis, hair follicles and sebaceous glands., KGF is also responsible for wound repair of various tissuesincluding lung, bladder, and kidney.

Chemical Properties

Molecular Weight

~18.7 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.