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GADD45A Protein, Human, Recombinant (His)
(Synonyms: Growth Arrest and DNA Damage-Inducible Protein GADD45 α, Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, GADD45A, GADD45, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, DDIT1) Copy Product InfoSynonyms: Growth Arrest and DNA Damage-Inducible Protein GADD45 α, Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, GADD45A, GADD45, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, DDIT1
Catalog No. TMPJ-00907 Copy Product Info
Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 35 days | 35 days | |
| 10 μg | $183 | 35 days | 35 days | |
| 20 μg | $292 | 35 days | 35 days | |
| 50 μg | $545 | 35 days | 35 days | |
| 100 μg | $792 | 35 days | 35 days | |
| 200 μg | $1,150 | 35 days | 35 days | |
| 500 μg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | P24522 |
| Amino Acid | Met1-Arg165 |
| Construction | Met1-Arg165 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Growth Arrest and DNA Damage-Inducible Protein GADD45 α, Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, GADD45A, GADD45, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, DDIT1 |
| Research Background |
| Molecular Weight | 18 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: GADD45A Protein, Human, Recombinant (His) chemical structure | GADD45A Protein, Human, Recombinant (His) molecular weight
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