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CYSLTR1 Protein, Human, Recombinant (His)

Catalog No. TMPH-03749
Synonyms: Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, Cysteinyl leukotriene D4 receptor, CysLTR1, CYSLTR1, CYSLT1, LTD4 receptor, HMTMF81

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 << LTE4 = LTC4 << LTB4.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CYSLTR1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 1,960.00
100 μg 20 days $ 3,210.00
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Biological Description
Technical Params
Product Properties
Description Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
Species Human
Expression System in vitro E. coli expression system
Tag N-terminal 10xHis-tagged
Accession Number Q9Y271
Synonyms Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, Cysteinyl leukotriene D4 receptor, CysLTR1, CYSLTR1, CYSLT1, LTD4 receptor, HMTMF81
Amino Acid MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 1-337 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 44.6 kDa (predicted)
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.

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Keywords

CYSLTR1 Protein, Human, Recombinant (His) Cysteinyl leukotriene receptor 1 G-protein coupled receptor HG55 Cysteinyl leukotriene D4 receptor CysLTR1 CYSLTR1 CYSLT1 LTD4 receptor HMTMF81 recombinant recombinant-proteins proteins protein

 

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