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Nonapeptide-1

Name: Nonapeptide-1
Brand: TargetMol
SKU: T7769
Price: 53 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7769Cas No. 158563-45-2

Alias Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-, Melanostatine™ 5

Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.

Nonapeptide-1

🥰Excellent

Catalog No. T7769Alias Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-, Melanostatine™ 5Cas No. 158563-45-2

Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$53	In Stock	In Stock
10 mg	$75	In Stock	In Stock
25 mg	$128	In Stock	In Stock
50 mg	$192	In Stock	In Stock
100 mg	$287	In Stock	In Stock
200 mg	$431	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.
Targets&IC50	MC5R:2.4 μM (Ki), MC1R:40 nM (Ki), MC3R:0.47 μM (Ki), MC4R:1.34 μM (Ki)
Synonyms	Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-, Melanostatine™ 5

Chemical Properties

Molecular Weight	1206.5
Formula	C₆₁H₈₇N₁₅O₉S
Cas No.	158563-45-2
Smiles	CSCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O
Relative Density.	1.38 g/cm3 (Predicted)
Sequence	Met-Pro-Phe-Arg-Trp-Phe-Lys-Pro-Val-NH2
Sequence Short	MPFRWFKPV-NH2

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120.65 mg/ml (100 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.8288 mL	4.1442 mL	8.2884 mL	41.4422 mL
5 mM	0.1658 mL	0.8288 mL	1.6577 mL	8.2884 mL
10 mM	0.0829 mL	0.4144 mL	0.8288 mL	4.1442 mL
20 mM	0.0414 mL	0.2072 mL	0.4144 mL	2.0721 mL
50 mM	0.0166 mL	0.0829 mL	0.1658 mL	0.8288 mL
100 mM	0.0083 mL	0.0414 mL	0.0829 mL	0.4144 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc