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Anti-CD2 Antibody (1O658)
😃Good
Catalog No. TMAY-01420
Alias T11, SRBC, LFA-2, CD2 molecule
Anti-CD2 Antibody (1O658) is a Mouse antibody targeting CD2. Anti-CD2 Antibody (1O658) can be used in IHC-P.
Anti-CD2 Antibody (1O658)
Anti-CD2 Antibody (1O658)
😃Good
Catalog No. TMAY-01420Alias T11, SRBC, LFA-2, CD2 molecule
Anti-CD2 Antibody (1O658) is a Mouse antibody targeting CD2. Anti-CD2 Antibody (1O658) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD2 Antibody (1O658) is a Mouse antibody targeting CD2. Anti-CD2 Antibody (1O658) can be used in IHC-P. |
| Alias | T11, SRBC, LFA-2, CD2 molecule |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1O658 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human CD2 in human spleen with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CD2 in human lymph node with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CD2 in human appendix with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD2 (rh CD2; TMPY-01255; NP_001758.2; Met1-Asp209). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, and SRBC, is a single-pass type I membrane protein. It contains one Ig-like C2-type domain and one Ig-like V-type domain. CD2 is a cell adhesion molecule expressed on T cells and is recognized as a target for CD48 (rats) and CD58 (humans). CD2 has been shown to set quantitative thresholds in T cell activation both in vivo and in vitro. Further, intracellular CD2 signaling pathways and networks are being discovered by the identification of several cytosolic tail binding proteins. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain of CD2 is implicated in the signaling function. The complex of CD2 and CD58 also plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. As a cell surface glycoprotein, CD2 expressed on most human T cells and natural killer (NK) cells and plays an important role in mediating cell adhesion in both T-lymphocytes and in signal transduction.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD2 protein (TMPY-01255) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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