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Anti-Cathepsin B Polyclonal Antibody

(Synonyms: cathepsin B) Copy Product Info
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Synonyms: cathepsin B

Catalog No. TMAB-00297 Copy Product Info
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Anti-Cathepsin B Polyclonal Antibody is a Rabbit antibody targeting Cathepsin B. Anti-Cathepsin B Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB.
Anti-Cathepsin B Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cathepsin B Polyclonal Antibody is a Rabbit antibody targeting Cathepsin B. Anti-Cathepsin B Polyclonal Antibody can be used in FCM,IF,IHC-Fr,WB.
Synonymscathepsin B
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1µg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cathepsin B heavy chain
Antigen Species
Human
Gene Name
CTSB
Gene ID
Protein Name
Cathepsin B
Uniprot ID
Biology Area
Cathespins,Cell adhesion,Extracellular matrix,Adhesion molecules ELISA kits,Membrane Proteins,Other Enzymes
Function
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Chemical Properties
Molecular WeightTheoretical: 23/28/37 kDa. Actual: 30 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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