SOST Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00102 Copy Product Info

SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.

SOST Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00102

Copy Product Info

SOST Protein, Human, Recombinant (His & Avi)

Pack Size	Price	USA Stock	Global Stock
5 μg	$56	7-10 days	7-10 days
10 μg	$88	7-10 days	7-10 days
20 μg	$143	7-10 days	7-10 days
50 μg	$278	7-10 days	7-10 days
100 μg	$465	7-10 days	7-10 days
200 μg	$839	7-10 days	7-10 days
500 μg	$1,850	7-10 days	7-10 days

Add to Cart

Add to Quotation

For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Resource Download

User Guide of Recombinant Proteins

Product Information

Biological Activity	Immobilized Human SOST, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SOST Antibody, hFc Tag with the EC50 of 6.3ng/ml determined by ELISA.
Description	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.
Species	Human
Expression System	HEK293 Cells
Tag	N-His-Avi
Accession Number	Q9BQB4-1
Synonyms	VBCHsclerosteosis,VBCH,SOST1,SOST,sclerostin,DAND6,CDD
Construction	Gln24-Tyr213
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	24.2 kDa (predicted). Due to glycosylation,the protein migrates to 28-40 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.