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Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16) Copy Product Info

Synonyms: IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16

Catalog No. TMPK-00598 Copy Product Info
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

Batch Information

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Purity:> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberAAH17865
ConstructionGly17-Gln208(V176)
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsIMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16
Research Background
Chemical Properties
Molecular Weight24.7 kDa (predicted). Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight