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Anti-LMNB1 Polyclonal Antibody (Synonyms: MCPH26, LMNB 1, LMNB, LMN2, LMN, Lamin-B1, ADLD)
Catalog No. TMAB-01077 Copy Product Info
🥰Excellent
Anti-LMNB1 Polyclonal Antibody is a Rabbit antibody targeting LMNB1. Anti-LMNB1 Polyclonal Antibody can be used in WB.
Anti-LMNB1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01077
Synonyms MCPH26, LMNB 1, LMNB, LMN2, LMN, Lamin-B1, ADLD
Anti-LMNB1 Polyclonal Antibody is a Rabbit antibody targeting LMNB1. Anti-LMNB1 Polyclonal Antibody can be used in WB.
Anti-LMNB1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-LMNB1 Polyclonal Antibody is a Rabbit antibody targeting LMNB1. Anti-LMNB1 Polyclonal Antibody can be used in WB. |
| Synonyms | MCPH26, LMNB 1, LMNB, LMN2, LMN, Lamin-B1, ADLD |
| Ig Type | IgG |
| Reactivity | Mouse |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with lamin B1 polyclonal antibody, unconjugated (TMAB-01077) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]. |
| Immunogen | KLH conjugated synthetic peptide: mouse Lamin B |
| Antigen Species | Mouse |
| Gene Name | LMNB1 |
| Gene ID | |
| Protein Name | Lamin-B1 |
| Uniprot ID | |
| Biology Area | Lamins,Lamins,Lamin B1 - Nuclear,Lamins,Nuclear Envelope |
| Function | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
| Molecular Weight | Theoretical: 64 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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