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Stepronin

Name: Stepronin
Brand: TargetMol
SKU: T21433
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21433Cas No. 72324-18-6

Alias TTPG, Tiofacic, Tiase, Prostenoglycine

Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.

Stepronin

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Purity: 99.59%

Catalog No. T21433Alias TTPG, Tiofacic, Tiase, ProstenoglycineCas No. 72324-18-6

Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$43	In Stock	In Stock
10 mg	$68	In Stock	In Stock
25 mg	$119	In Stock	In Stock
50 mg	$208	In Stock	In Stock
100 mg	$323	-	In Stock
200 mg	$456	-	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.59%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.
In vitro	In canine tracheal epithelium, Stepronin (0.1-100 µM) dose-dependently reduces Isoproterenol-evoked short circuit current value, the basal secretion and Isoproterenol-evoked potential difference value[1]. In submucosal glands, Stepronin (100 µM) causes the potent inhibition of Isoproterenol-induced [3H]-glycoconjugate secretion[3].
Synonyms	TTPG, Tiofacic, Tiase, Prostenoglycine

Chemical Properties

Molecular Weight	273.33
Formula	C₁₀H₁₁NO₄S₂
Cas No.	72324-18-6
Smiles	CC(SC(=O)c1cccs1)C(=O)NCC(O)=O
Relative Density.	1.428 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (823.18 mM), Sonication is recommended.

H2O: Insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6586 mL	18.2929 mL	36.5858 mL	182.9291 mL
5 mM	0.7317 mL	3.6586 mL	7.3172 mL	36.5858 mL
10 mM	0.3659 mL	1.8293 mL	3.6586 mL	18.2929 mL
20 mM	0.1829 mL	0.9146 mL	1.8293 mL	9.1465 mL
50 mM	0.0732 mL	0.3659 mL	0.7317 mL	3.6586 mL
100 mM	0.0366 mL	0.1829 mL	0.3659 mL	1.8293 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc