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PF-1163B
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Catalog No. T28379Cas No. 258871-60-2
Alias PF1163B, PF 1163B, (-)-PF1163B
PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells.
PF-1163B
😃Good
Catalog No. T28379Alias PF1163B, PF 1163B, (-)-PF1163BCas No. 258871-60-2
PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2500 μg | $1,880 | 35 days |
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Chemical Properties
| Description | PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells. |
| Synonyms | PF1163B, PF 1163B, (-)-PF1163B |
| Molecular Weight | 461.63 |
| Formula | C27H43NO5 |
| Cas No. | 258871-60-2 |
| Relative Density. | 1.027 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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