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B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)

(Synonyms: β-2 microglobulin, beta-2 microglobulin) Copy Product Info

Synonyms: β-2 microglobulin, beta-2 microglobulin

Catalog No. TMPY-01686 Copy Product Info
Purity: 98.1%
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P61769-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$35-In Stock
10 µg$52-In Stock
20 µg$81-In Stock
50 µg$1537-10 days7-10 days
100 µg$255-In Stock
200 µg$4517-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.1%
Appearance:Lyophilized powder
Color:White
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Product Information

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is P61769-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP61769-1
ConstructionIle21-Met119
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
B2M/beta 2-Microglobulin Protein, Human, Recombinant (His),B2M/beta 2-Microglobulin Protein, Human, Recombinant (His)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonymsβ-2 microglobulin, beta-2 microglobulin
Research Background
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.
Chemical Properties
Molecular Weight12.8 kDa (Predicted); 13-15 kDa (Reducing conditions due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) chemical structure | B2M/beta 2-Microglobulin Protein, Human, Recombinant (His) molecular weight