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Anti-JAM-A Antibody-PE (5E755)
🥰Excellent
Catalog No. TMAY-00440P
Anti-JAM-A Antibody-PE (5E755) is a PE-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-PE (5E755) can be used in FCM.
Anti-JAM-A Antibody-PE (5E755)
Anti-JAM-A Antibody-PE (5E755)
🥰Excellent
Catalog No. TMAY-00440P
Anti-JAM-A Antibody-PE (5E755) is a PE-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-PE (5E755) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-JAM-A Antibody-PE (5E755) is a PE-conjugated Mouse antibody targeting JAM-A. Anti-JAM-A Antibody-PE (5E755) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5E755 |
| Reactivity | Human |
| Verified Activity | Profile of anti-JAM-A (CD321) reactivity on SKBR3 cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human JAM-A / F11R / CD321 (rh JAM-A / F11R / CD321; TMPY-01035; NP_058642.1; Met 1-Ala 242) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human JAM-A / F11R / CD321 protein (TMPY-01035) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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