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Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His)
(Synonyms: Trfr, transferrin receptor, TR, TFR1, TFR, p90, Mtvr-1, Mtvr1, E430033M20Rik, CD71, AU015758, AI426448, AI195355, 2610028K12Rik) Copy Product InfoSynonyms: Trfr, transferrin receptor, TR, TFR1, TFR, p90, Mtvr-1, Mtvr1, E430033M20Rik, CD71, AU015758, AI426448, AI195355, 2610028K12Rik
Catalog No. TMPY-02294 Copy Product Info
Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.3 kDa and the accession number is Q62351.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $55 | - | In Stock | |
| 10 µg | $86 | - | In Stock | |
| 20 µg | $139 | - | In Stock | |
| 50 µg | $269 | - | In Stock | |
| 100 µg | $451 | 7-10 days | 7-10 days | |
| 200 µg | $798 | 7-10 days | 7-10 days | |
| 500 µg | $1,690 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:94.4%
Appearance:Lyophilized powder
Color:White
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| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.3 kDa and the accession number is Q62351. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | Q62351 |
| Construction | A DNA sequence encoding the extracellular domain of mouse TFRC (Q62351) (Cys 89-Phe 763) was fused with a polyhistidine tag at the N-terminus. Predicted N terminal: His |
| Protein Purity | > 92 % as determined by SDS-PAGE  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 150 mM NaCl, 5% Mannitol, 0.1% Tween 80, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | Trfr, transferrin receptor, TR, TFR1, TFR, p90, Mtvr-1, Mtvr1, E430033M20Rik, CD71, AU015758, AI426448, AI195355, 2610028K12Rik |
| Research Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Molecular Weight | 78.3 kDa (predicted); 80 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) chemical structure | Transferrin Receptor/TFRC Protein, Mouse, Recombinant (His) molecular weight
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