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Paeonoside
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Catalog No. TN6926Cas No. 20309-70-0
Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death from sepsis. Paeonoside has no cytotoxic effect on preosteoblasts of MC3T3-E1 cells, significantly restores the wound area and promotes cell migration and alkaline phosphatase (ALP) staining and its activity in a dose-dependent manner.
Paeonoside
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Purity: 99.98%
Catalog No. TN6926Cas No. 20309-70-0
Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death from sepsis. Paeonoside has no cytotoxic effect on preosteoblasts of MC3T3-E1 cells, significantly restores the wound area and promotes cell migration and alkaline phosphatase (ALP) staining and its activity in a dose-dependent manner.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $117 | - | In Stock | |
| 5 mg | $293 | - | In Stock | |
| 10 mg | $429 | - | In Stock | |
| 25 mg | $653 | - | In Stock | |
| 50 mg | $888 | - | In Stock | |
| 100 mg | $1,180 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $289 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.98%
Appearance:Solid
Color:Yellow
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death from sepsis. Paeonoside has no cytotoxic effect on preosteoblasts of MC3T3-E1 cells, significantly restores the wound area and promotes cell migration and alkaline phosphatase (ALP) staining and its activity in a dose-dependent manner. |
| In vitro | Paeonoside (0.1-100 μM, 24 h) exhibited no cytotoxicity towards MC3T3-E1 pro-osteoblasts cells, even at concentrations ranging from 0.1 to 100 μM, when treated for 24 hours.[1] When MC3T3-E1 preosteoblasts were induced to differentiate using osteogenic supplement (OS) medium, treatment with PASI (1-30 μM, 24 h) significantly enhanced wound area restoration and facilitated cell migration in a dose-dependent manner. Furthermore, PASI demonstrated a dose-dependent promotion of alkaline phosphatase (ALP) staining and activity.[1] |
| Molecular Weight | 328.31 |
| Formula | C15H20O8 |
| Cas No. | 20309-70-0 |
| Smiles | O(C1=C(C(C)=O)C=CC(OC)=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O |
| Relative Density. | 1.414 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (68.53 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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