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Anti-Mesothelin Antibody (6G41)

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Catalog No. TMAY-02493
Alias mesothelin

Anti-Mesothelin Antibody (6G41) is a Mouse antibody targeting Mesothelin. Anti-Mesothelin Antibody (6G41) can be used in ELISA,IHC-P.

Anti-Mesothelin Antibody (6G41)

Anti-Mesothelin Antibody (6G41)

😃Good
Catalog No. TMAY-02493Alias mesothelin
Anti-Mesothelin Antibody (6G41) is a Mouse antibody targeting Mesothelin. Anti-Mesothelin Antibody (6G41) can be used in ELISA,IHC-P.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Mouse Monoclonal

Application: ELISA, IHC-P

Reactivity: Human
Aliasmesothelin
Ig Type
Mouse IgG2a
Clone
6G41
Reactivity
Human
Verified Activity
1. Immunochemical staining of human Mesothelin in human ovarian cancer with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human Mesothelin in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Application
ELISA,IHC-P
Recommended Dose
ELISA: 1:1000-1:2000; IHC-P: 1:30-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Mesothelin / MSLN (rh Mesothelin / MSLN; TMPY-00132; NP_005814.2; Glu296-Gly580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human Mesothelin / MSLN Protein (TMPY-00132)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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