Shopping Cart
Remove All
Your shopping cart is currently empty
Nocloprost
😃Good
Catalog No. T33710Cas No. 79360-43-3
Alias ZK94726, ZK84726, ZK 94726, ZK 84726, SH475, SH 475
Nocloprost (SH 475) is a prostaglandin E2 (PGE2) analog, an EP1 and EP3 receptor agonist with local gastric protection and ulcer healing activity, reducing aspirin-induced gastrointestinal lesions, and inducing platelet activation, useful for studying cardiovascular diseases.
Nocloprost
😃Good
Catalog No. T33710Alias ZK94726, ZK84726, ZK 94726, ZK 84726, SH475, SH 475Cas No. 79360-43-3
Nocloprost (SH 475) is a prostaglandin E2 (PGE2) analog, an EP1 and EP3 receptor agonist with local gastric protection and ulcer healing activity, reducing aspirin-induced gastrointestinal lesions, and inducing platelet activation, useful for studying cardiovascular diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $218 | - | In Stock | |
| 500 μg | $589 | - | In Stock | |
| 1 mg | $855 | 35 days | 35 days |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Appearance:Liquid
Color:Transparent
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Nocloprost (SH 475) is a prostaglandin E2 (PGE2) analog, an EP1 and EP3 receptor agonist with local gastric protection and ulcer healing activity, reducing aspirin-induced gastrointestinal lesions, and inducing platelet activation, useful for studying cardiovascular diseases. |
| In vitro | In platelet-rich citrate plasma, Nocloprost (> 0.1 mumol/l) causes aggregation of biphasic processes at higher concentrations. Nocloprost activation of platelets is accompanied by thromboxen A2 formation and an increase in cytoplasmic calcium in platelets containing Indo 1. Nocloprost(0.1 μM/L) enhanced aggregation induced by low concentrations of ADP or adrenaline. [2] |
| In vivo | Nocloprost (0.01-100 μg/kg, intragastric administration) is dose-dependent in preventing the formation of gastric lesions. Nocloprost (0.01-100 μg/kg, gavage) did not affect gastric acid secretion or intestinal secretion in rats, but prevented the increase of gastroduodenal alkaline secretion. [1] |
| Synonyms | ZK94726, ZK84726, ZK 94726, ZK 84726, SH475, SH 475 |
| Molecular Weight | 400.98 |
| Formula | C22H37ClO4 |
| Cas No. | 79360-43-3 |
| Smiles | C(=C/[C@H](C(CCCC)(C)C)O)\[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@H](Cl)C[C@H]1O |
| Relative Density. | 1.1g/cm3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Nocloprost | purchase Nocloprost | Nocloprost cost | order Nocloprost | Nocloprost chemical structure | Nocloprost in vivo | Nocloprost in vitro | Nocloprost formula | Nocloprost molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.