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Anti-LDLR Antibody-APC (9A669)

🥰Excellent
Catalog No. TMAY-00501A

Anti-LDLR Antibody-APC (9A669) is a APC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-APC (9A669) can be used in FCM.

Anti-LDLR Antibody-APC (9A669)

Anti-LDLR Antibody-APC (9A669)

🥰Excellent
Catalog No. TMAY-00501A
Anti-LDLR Antibody-APC (9A669) is a APC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-APC (9A669) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-LDLR Antibody-APC (9A669) is a APC-conjugated Rabbit antibody targeting LDLR. Anti-LDLR Antibody-APC (9A669) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
9A669
Reactivity
Human
Verified Activity
Profile of anti-Human LDLR reactivity on A431 cells analyzed by flow cytometry.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human LDL Receptor / LDLR (rh LDL Receptor / LDLR; TMPY-00989; NP_000518.1; Met 1-Arg 788) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundLDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDL Receptor consists of 840 amino acids (after removal of signal peptide) and mediates the endocytosis of cholesterol-rich LDL. Low-density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. LDL Receptor is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human LDL Receptor / LDLR protein (TMPY-00989)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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