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Synonyms: NPY-Y2 receptor (Y2 receptor), NPY2-R, NPY2R, Neuropeptide Y receptor type 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-NPY2R Polyclonal Antibody is a Rabbit antibody targeting NPY2R. Anti-NPY2R Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | NPY-Y2 receptor (Y2 receptor), NPY2-R, NPY2R, Neuropeptide Y receptor type 2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Pig) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Neuropeptide Y (NPY), a peptide widely expressed in the brain, acts through the protein G-coupled receptors Y1, Y2 and Y5. This peptide modulates many important functions such as the control of energy balance and anxiety. Its involvement in brain development has been less investigated. Neuropeptide Y (NPY) receptors are members of a G protein coupled receptor superfamily and they mediate a variety of physiological responses including feeding and vasoconstriction. The endogenous ligands of NPY receptors are a family of structurally related peptides, including NPY, peptide YY (PYY), and pancreatic polypeptide (PP). Increased activity of NPY and its receptors, Y1R, Y2R, and Y5R has been found in the brain in many forms of experimental obesity. Furthermore, several association studies have supported the association between NPY2R and obesity. |
| Immunogen | KLH conjugated synthetic peptide: human NPY2R |
| Antigen Species | Human |
| Gene Name | NPY2R |
| Gene ID | |
| Protein Name | Neuropeptide Y receptor type 2 |
| Uniprot ID | |
| Biology Area | Angiogenic Factors,Diabetes associated,Lipoprotein metabolism,Lipoprotein metabolism,Cancer,Diabetes,Heart disease,Receptors,More GPCR |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. |
| Molecular Weight | Theoretical: 43 kDa. Actual: 43 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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