Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 105.00 | |
25 mg | In stock | $ 222.00 | |
50 mg | In stock | $ 333.00 | |
100 mg | In stock | $ 498.00 | |
500 mg | In stock | $ 1,130.00 |
Description | 7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to study signalling pathways related to immunity and cancer. |
In vitro |
In the PRESTO-Tango assay, 7-FluorotryptaMine HCl (100 μM) hydrochloride induces GPRC5A recruitment of β-arrestin.[1] Co-treatment with 7-FluorotryptaMine HCl (50 μM, 8 h) and TNFα downregulates TNFα-induced genes (e.g., IL41A, CXCL10, CSF2) in WT and GPRC5A-KO cells [1]. 7-FluorotryptaMine HCl (0-100 μM, 16 h) is not toxic to mammalian cells (HTLA, HT-29 cells).[1] |
Molecular Weight | 214.67 |
Formula | C10H12ClFN2 |
CAS No. | 159730-09-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 21.47 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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7-FluorotryptaMine HCl 159730-09-3 Endocrinology/Hormones GPCR/G Protein Arrestin GPR 7FluorotryptaMineHCl inhibitor inhibit