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Anti-PD-L2 Antibody-FITC (3W144)
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Catalog No. TMAY-00569F
Alias programmed cell death 1 ligand 2
Anti-PD-L2 Antibody-FITC (3W144) is a FITC-conjugated Rabbit antibody targeting PD-L2. Anti-PD-L2 Antibody-FITC (3W144) can be used in FCM.
Anti-PD-L2 Antibody-FITC (3W144)
Anti-PD-L2 Antibody-FITC (3W144)
😃Good
Catalog No. TMAY-00569FAlias programmed cell death 1 ligand 2
Anti-PD-L2 Antibody-FITC (3W144) is a FITC-conjugated Rabbit antibody targeting PD-L2. Anti-PD-L2 Antibody-FITC (3W144) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $105 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PD-L2 Antibody-FITC (3W144) is a FITC-conjugated Rabbit antibody targeting PD-L2. Anti-PD-L2 Antibody-FITC (3W144) can be used in FCM. |
| Alias | programmed cell death 1 ligand 2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3W144 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human PDL2(CD273) expression on monocyte-derived dendritic cells. Cells were stained with FITC-conjugated anti-Human PDL2(CD273). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human B7-DC / PD-L2 / CD273 / PDCD1LG2 (rh B7-DC / PD-L2 / CD273 / PDCD1LG2; TMPY-04346; NP_079515.2; Met1-Pro219) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | FITC |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human B7-DC / PD-L2 / CD273 / PDCD1LG2 Protein (TMPY-04346) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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