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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody
(Synonyms: SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)) Copy Product Info
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Synonyms: SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)
Catalog No. TMAC-03812 Copy Product Info
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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB.
Anti-Phospho-SNAI1
(Ser246) Polyclonal Antibody
(Ser246) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB. |
| Synonyms | SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 246 (T-F-S(p)-R-M) derived from Human SNAI1 |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Actual: 29 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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