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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody (Synonyms: SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246)|...)

Catalog No. TMAC-03812 Copy Product Info
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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB.

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-03812
Synonyms SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB.

Anti-Phospho-SNAI1
(Ser246) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB.
SynonymsSNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from Rat heart tissue using SNAI1 (Phospho-Ser246) Antibody Antibody TMAC-03812. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundInvolved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine 246 (T-F-S(p)-R-M) derived from Human SNAI1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 29 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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