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Fumarase Protein, Human, Recombinant

(Synonyms: Fumarate Hydratase Mitochondrial, Fumarase, FH) Copy Product Info

Synonyms: Fumarate Hydratase Mitochondrial, Fumarase, FH

Catalog No. TMPJ-00313 Copy Product Info
Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1127-10 days7-10 days
10 μg$1837-10 days7-10 days
20 μg$2927-10 days7-10 days
50 μg$5457-10 days7-10 days
100 μg$7927-10 days7-10 days
200 μg$1,1507-10 days7-10 days
500 μg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase is thought to act as a tumor suppressor, which deficiency can lead to progressive encephalopathy, cerebral atrophy and development delay.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP07954
Amino AcidAla45-Lys510
ConstructionAla45-Lys510
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.0.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsFumarate Hydratase Mitochondrial, Fumarase, FH
Research Background
Chemical Properties
Molecular Weight45 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Related Tags: Fumarase Protein, Human, Recombinant chemical structure | Fumarase Protein, Human, Recombinant molecular weight