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(S)-(+)-Niguldipine hydrochloride

🥰Excellent
TargetMol
Catalog No. T23301Cas No. 113145-69-0

(S)-(+)-Niguldipine hydrochloride is a selective α1A-AR antagonist used in the study of depression and epilepsy.

(S)-(+)-Niguldipine hydrochloride
Other Forms of (S)-(+)-Niguldipine hydrochloride:

(S)-(+)-Niguldipine hydrochloride

🥰Excellent
TargetMol
Purity: 98.27%
Catalog No. T23301Cas No. 113145-69-0
(S)-(+)-Niguldipine hydrochloride is a selective α1A-AR antagonist used in the study of depression and epilepsy.
Pack SizePriceAvailabilityQuantity
1 mg$75In Stock
5 mg$179In Stock
10 mg$263In Stock
25 mg$619In Stock
50 mg$1,080In Stock
100 mg$1,450In Stock
500 mg$2,890In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:98.27%
ee:100%
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Product Introduction

Bioactivity
Description
(S)-(+)-Niguldipine hydrochloride is a selective α1A-AR antagonist used in the study of depression and epilepsy.
Chemical Properties
Molecular Weight646.17
FormulaC36H40ClN3O6
Cas No.113145-69-0
SmilesC(CCOC(=O)C=1[C@H](C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2)N3CCC(CC3)(C4=CC=CC=C4)C5=CC=CC=C5.Cl
Relative Density.1.31g/cm3
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: <64.62 mg/mL, Sonication is recommended.
Ethanol: <64.62 mg/mL, Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

α1-adrenergic receptorNiguldipine HydrochlorideAdrenergicReceptorAdrenergic Receptor(S)(+)Niguldipine hydrochloride(S) (+) Niguldipine hydrochloride
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