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Anti-ALOX15 Polyclonal Antibody 2
(Synonyms: LOX15, LOG15, Arachidonate omega 6 lipoxygenase, Arachidonate 15 lipoxygenase, 15LOX 1, 15-LOX, 15 LOX 1, 15 LOX, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 lipoxygenase 1) Copy Product Info
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Synonyms: LOX15, LOG15, Arachidonate omega 6 lipoxygenase, Arachidonate 15 lipoxygenase, 15LOX 1, 15-LOX, 15 LOX 1, 15 LOX, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 lipoxygenase 1
Catalog No. TMAB-00099 Copy Product Info
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Anti-ALOX15 Polyclonal Antibody 2 is a Rabbit antibody targeting ALOX15. Anti-ALOX15 Polyclonal Antibody 2 can be used in IF, IHC-Fr, IHC-P, WB.
Anti-ALOX15 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ALOX15 Polyclonal Antibody 2 is a Rabbit antibody targeting ALOX15. Anti-ALOX15 Polyclonal Antibody 2 can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | LOX15, LOG15, Arachidonate omega 6 lipoxygenase, Arachidonate 15 lipoxygenase, 15LOX 1, 15-LOX, 15 LOX 1, 15 LOX, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 lipoxygenase 1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Application | |
| Recommended Dose | IF=1:50-300; IHC-Fr=1:50-300; IHC-P=1:50-300; WB=1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Skeletal muscle and brain (cerebellum and hippocampus). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation. |
| Immunogen | KLH conjugated synthetic peptide: human ALOX15 |
| Antigen Species | Human |
| Gene Name | ALOX15 |
| Gene ID | |
| Protein Name | Polyunsaturated fatty acid lipoxygenase ALOX15 |
| Uniprot ID | |
| Biology Area | Tumor biomarkers,Lipoprotein metabolism,Metabolism,Fatty acids,Lipoprotein metabolism,Fatty acid oxidation,Heart disease,Hormones |
| Function | Oxygenase and 14,15-leukotriene A4 synthase activity. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. |
| Molecular Weight | Theoretical: 75 kDa. Actual: 77 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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