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Anti-OX40/TNFRSF4 Antibody-PE (9R426)

🥰Excellent
Catalog No. TMAY-03472P

Anti-OX40/TNFRSF4 Antibody-PE (9R426) is a PE-conjugated Rabbit antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (9R426) can be used in FCM.

Anti-OX40/TNFRSF4 Antibody-PE (9R426)

Anti-OX40/TNFRSF4 Antibody-PE (9R426)

🥰Excellent
Catalog No. TMAY-03472P
Anti-OX40/TNFRSF4 Antibody-PE (9R426) is a PE-conjugated Rabbit antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (9R426) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-OX40/TNFRSF4 Antibody-PE (9R426) is a PE-conjugated Rabbit antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody-PE (9R426) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
9R426
Reactivity
Mouse
Verified Activity
Flow cytometric analysis of Mouse-OX40 expression on ConA-stimulated BABL/c splenocytesCells were stained with PE-conjugated anti-Mouse-OX40. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse OX40 (rM OX40; TMPY-05020; NP_035789.1; Met1-Pro211) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundOX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/FITC
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Mouse OX40 Protein (TMPY-05020)
Antigen Species
Mouse
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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