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TargetMol | Compound Library

Covalent Natural Product Library

Catalog No. L6150

Natural products have been proven to demonstrate their success in modulating certain isolated but important targets, such as a range of antimicrobial targets, in particular protein-protein interactions. Therefore, many researchers consider natural products and their derivatives as unique tools for the study and manipulation of protein function.

Covalent compounds, a class of organic small molecules, can interact with specific target proteins and form covalent bonds, resulting in a change in protein conformation that inhibits protein activity. Except for some rare cases, protein modifications by covalent interactions are usually irreversible.

TargetMol Natural Product Covalent Library carefully screens 745 covalent compounds of natural products, which have not only the characteristics of natural products but also the mechanism of action of covalent compounds, and are cost-effective and powerful tools for drug development, pharmacological studies, stem cell differentiation, fingerprinting studies, quality studies and other fields.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6150

Covalent Natural Product Library

sizeIn stock

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
  • Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research.
  • Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information.
  • Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost.
  • Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc.

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Library Customization | TargetMol Library Composition

Endogenous Metabolite
Apoptosis
Antibacterial
NF-κB
Autophagy
ROS
Antibiotic
Antifungal
Reactive Oxygen Species
Parasite
Akt
COX
p38 MAPK
Interleukin
Antioxidant
Caspase
Influenza Virus
ERK
Cytochromes P450
PI3K
Nrf2
NO Synthase
STAT
Anti-infection
DNA/RNA Synthesis
Microtubule Associated
Calcium Channel
JNK
Dehydrogenase
TNF
HIV Protease
Ferroptosis
MMP
Bcl-2 Family
AMPK
GABA Receptor
HIF/HIF Prolyl-Hydroxylase
Cholinesterase (ChE)
Tyrosinase
NOD-like Receptor (NLR)
ATPase
PKC
P-gp
SARS-CoV
Virus Protease
CDK
VEGFR
TRP/TRPV Channel
HSV
IL Receptor
NOS
PPAR
Wnt/beta-catenin
glycosidase
Estrogen/progestogen Receptor
Reductase
Immunology/Inflammation related
Drug Metabolite
JAK
Lipoxygenase
TGF-beta/Smad
Prostaglandin Receptor
Beta Amyloid
AChR
Phosphatase
GSK-3
PKA
HBV
PARP
Adrenergic Receptor
Glucocorticoid Receptor
Androgen Receptor
Antiviral
TLR
IκB/IKK
Sodium Channel
Proteasome
Src
PERK
Mitophagy
Estrogen Receptor/ERR
FXR
PDE
Glucosidase
Mitochondrial Metabolism
Antifection
Angiotensin-converting Enzyme (ACE)
Epigenetic Reader Domain
CaMK
mTOR
EGFR
Lipid
MAPK
HSP
Sirtuin
Pyroptosis
HDAC
ribosome
Ras
RAAS
Progesterone Receptor
MAO
iGluR
IAP
Topoisomerase
Opioid Receptor
Telomerase
Aromatase
Potassium Channel
HMG-CoA Reductase
p53
PD-1/PD-L1
Monoamine Oxidase
Chloride channel
Transferase
Dopamine Receptor
Histone Methyltransferase
ADC Cytotoxin
BACE
Serine Protease
Nucleoside Antimetabolite/Analog
UGT
Gamma-secretase
Smo
Hedgehog/Smoothened
Stearoyl-CoA Desaturase (SCD)
CXCR
Cadherin
IGF-1R
OXPHOS
Survivin
Retinoid Receptor
Phospholipase
Oxytocin Receptor
HIF
DNA Methyltransferase
Thrombin
ROS Kinase
AhR
Mdm2
Proton pump
Carbonic Anhydrase
Transaminase
RAR/RXR
DNA-PK
HCV Protease
Integrin
DNA Alkylator/Crosslinker
Adenosine Receptor
Arrestin
IFNAR
Lipase
Histamine Receptor
Galectin
c-Myc
MRP
Tyrosine Kinases
Photosensitizer
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
RANKL/RANK
Aryl Hydrocarbon Receptor
IRE1
Adenylate cyclase
E1/E2/E3 Enzyme
Bcr-Abl
PAFR
Raf
Glucagon Receptor
P2X Receptor
NMDAR
Monoamine Transporter
Fatty Acid Synthase
PDGFR
CCR
PTEN
Xanthine Oxidase
ATP Citrate Lyase
Beta-Secretase
PGE Synthase
Glutathione reductase
Acyltransferase
Free radical scavengers
Histone Acetyltransferase
AIM2
CPT
transporter
RSV
Casein Kinase
ATM/ATR
FKBP
TMV
CRISPR/Cas9
Aquaporin
FOXO
Adenosine Deaminase
PLK
FGFR
MEK
Cuproptosis
Complement System
MDM-2/p53
Platelet aggregation
Syk
NOD
S6 Kinase
Tight Junction Protein
FAK
S1P Receptor
HER
PKM
Vitamin
ADC Linker

Keywords