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TargetMol | Compound Library

Covalent Natural Product Library

Catalog No. L6150

Natural products have been proven to demonstrate their success in modulating certain isolated but important targets, such as a range of antimicrobial targets, in particular protein-protein interactions. Therefore, many researchers consider natural products and their derivatives as unique tools for the study and manipulation of protein function.

Covalent compounds, a class of organic small molecules, can interact with specific target proteins and form covalent bonds, resulting in a change in protein conformation that inhibits protein activity. Except for some rare cases, protein modifications by covalent interactions are usually irreversible.

TargetMol Natural Product Covalent Library carefully screens 1173 covalent compounds of natural products, which have not only the characteristics of natural products but also the mechanism of action of covalent compounds, and are cost-effective and powerful tools for drug development, pharmacological studies, stem cell differentiation, fingerprinting studies, quality studies and other fields.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6150

Covalent Natural Product Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.
 Covalent Natural Product Library

Product Description Product Description

  • Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
  • Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research.
  • Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information.
  • Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost.
  • Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc.

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Library Customization | TargetMol Library Composition

Apoptosis
Endogenous Metabolite
Antibacterial
NF-κB
ROS
Autophagy
Antifungal
Antibiotic
Antioxidant
Parasite
COX
NO Synthase
Reactive Oxygen Species
Akt
p38 MAPK
Interleukin
TNF
HIV Protease
Nrf2
Calcium Channel
Cytochromes P450
Caspase
Microtubule Associated
ERK
IL Receptor
Influenza Virus
PI3K
DNA/RNA Synthesis
AChR
STAT
Anti-infection
Ferroptosis
Bcl-2 Family
AMPK
ATPase
HIF/HIF Prolyl-Hydroxylase
JNK
PPAR
Immunology/Inflammation related
Glucosidase
MMP
P-gp
Cholinesterase (ChE)
Wnt/beta-catenin
Dehydrogenase
Beta Amyloid
Tyrosinase
HBV
mTOR
Potassium Channel
NOS
Topoisomerase
glycosidase
SARS-CoV
Antiviral
Virus Protease
PKC
HSV
JAK
GABA Receptor
NOD-like Receptor (NLR)
Adrenergic Receptor
CDK
Antifection
TGF-beta/Smad
HSP
TLR
Prostaglandin Receptor
Sodium Channel
Phosphatase
Estrogen Receptor/ERR
VEGFR
TRP/TRPV Channel
Mitochondrial Metabolism
Sirtuin
Androgen Receptor
HCV Protease
GSK-3
PARP
Drug Metabolite
Lipoxygenase
EGFR
5-HT Receptor
ADC Cytotoxin
RAAS
c-Myc
PDE
Pyroptosis
Src
Reductase
Transferase
PERK
Glucocorticoid Receptor
Cysteine Protease
Angiotensin-converting Enzyme (ACE)
MAPK
Survivin
IκB/IKK
GST
Phospholipase
HIF
NOD
Ras
Liposome
Monoamine Oxidase
Chloride channel
Estrogen/progestogen Receptor
Dopamine Receptor
MAO
UGT
Gamma-secretase
CaMK
Lipid
HMG-CoA Reductase
Reverse Transcriptase
Aromatase
PD-1/PD-L1
Carbonic Anhydrase
c-Met/HGFR
BACE
Proton pump
LTR
Histone Demethylase
Lipase
Mitophagy
Serine/threonin kinase
Amylase
MRP
FXR
PAFR
P2X Receptor
GlyT
Monoamine Transporter
Fatty Acid Synthase
Chk
Xanthine Oxidase
transporter
ATM/ATR
ribosome
MDM-2/p53
FKBP
HDAC
Oxytocin Receptor
PLK
Platelet aggregation
Syk
FAK
Transaminase
Monocarboxylate transporter
DNA-PK
CRM1
DNA Alkylator/Crosslinker
Arrestin
gp120/CD4
Glutathione Peroxidase
Progesterone Receptor
Thyroid hormone receptor(THR)
Melanin-concentrating Hormone Receptor (MCHR)
Proteasome
Mdm2
MicroRNA
NPC1L1
RAR/RXR
Integrin
Necroptosis
Galectin
PKA
ASCT
Photosensitizer
Serine Protease
RANKL/RANK
iGluR
Annexin A
Adiponectin Receptor
Bcr-Abl
Fas/FasL
LDL
Phosphorylase
ATG
LDLR
NR4A
Aryl Hydrocarbon Receptor
Adenylate cyclase
E1/E2/E3 Enzyme
Glucagon Receptor
Opioid Receptor
Vasopressin Receptor
CXCR
Epigenetic Reader Domain
PANoptosis
DUB
Beta-Secretase
PGE Synthase
Glutathione reductase
CPT
FAAH
PTEN
Telomerase
OAT
Aminopeptidase
p62
TMV
MEK
Tight Junction Protein
AhR
RSV
Retinoid Receptor
Melanocortin Receptor
CRISPR/Cas9
FOXO
Gap Junction Protein
ROS Kinase
p53
S1P Receptor
HER
Vitamin

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