MDC/CCL22 Protein, Mouse, Recombinant (His)

Name: MDC/CCL22 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-00305
Price: 63 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Scya22, MDC, DCBCK, chemokine (C-C motif) ligand 22, ABCD-1) Copy Product Info

Synonyms: Scya22, MDC, DCBCK, chemokine (C-C motif) ligand 22, ABCD-1

Catalog No. TMPY-00305 Copy Product Info

MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number is O88430.

MDC/CCL22 Protein, Mouse, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$63	-	In Stock
10 µg	$98	-	In Stock
20 µg	$163	-	In Stock
50 µg	$323	-	In Stock
100 µg	$625	-	In Stock
200 µg	$939	7-10 days	7-10 days
500 µg	$1,970	7-10 days	7-10 days
1 mg	$3,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95 % as determined by SDS-PAGE

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	MDC Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 9.9 kDa and the accession number is O88430.
Species	Mouse
Expression System	E. coli
Tag	N-His
Accession Number	O88430
Construction	A DNA sequence encoding the mouse CCL22 (O88430) (Gly26-Ser92) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 0.1% TFA, 50% acetonitrile. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	Scya22, MDC, DCBCK, chemokine (C-C motif) ligand 22, ABCD-1
Research Background	Chemokine (C-C motif) ligand 22(ABCD-1 / CCL22)is a kind of CC chemokine which is a family of secreted proteins involved in immunoregulatory and inflammatory processes. The cytokine displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. This ABCD-1 / CCL22 chemokine binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated / effector T lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. ABCD-1 / CCL22 is highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus, and in Langerhans' cell histiocytosis and atopic dermatitis but not in dermatopathic lymphadenopathy. This chemokine is also found in lymph node, appendix, activated monocytes, resting and activated macrophages. This protein is lower expressed in lung and spleen and very weekly expressed in small intestine.

Chemical Properties

Molecular Weight

9.9 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.