AP1867-2-(carboxymethoxy)

Name: AP1867-2-(carboxymethoxy)
Brand: TargetMol
SKU: T18611
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Catalog No. T18611Cas No. 2230613-03-1

Alias PROTAC FKBP12-binding moiety 2

AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].

AP1867-2-(carboxymethoxy)

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Catalog No. T18611Alias PROTAC FKBP12-binding moiety 2Cas No. 2230613-03-1

AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].

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2 mg	$284	5 days	5 days

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Product Introduction

Bioactivity

Description	AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
In vitro	dTAG molecules engage FKBP12F36V and CRBN[1].
Synonyms	PROTAC FKBP12-binding moiety 2

Chemical Properties

Molecular Weight	693.78
Formula	C₃₈H₄₇NO₁₁
Cas No.	2230613-03-1
Relative Density.	1.214 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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