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Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody

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Catalog No. TMAC-02146

Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL-4R (Tyr497). Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.

Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody

Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody

😃Good
Catalog No. TMAC-02146
Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL-4R (Tyr497). Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL-4R (Tyr497). Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:5000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundinterleukin 4 receptor(IL4R) Homo sapiens This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human IL-4R/CD124 around the phosphorylation site of Tyr497. AA range:463-512
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 90 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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