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Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL-4R (Tyr497). Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IL-4R (Tyr497). Anti-Phospho-IL-4R (Tyr497) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse |
Application | |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:5000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | interleukin 4 receptor(IL4R) Homo sapiens This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012], |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human IL-4R/CD124 around the phosphorylation site of Tyr497. AA range:463-512 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 90 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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