PRDX5 Protein, Human, Recombinant (His)

Name: PRDX5 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00933
Price: 72 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TPx type VI, Thioredoxin reductase, Thioredoxin peroxidase PMP20, Prx-V, PRDX5, PLP, Peroxisomal antioxidant enzyme, Peroxiredoxin-5, Peroxiredoxin V, Liver tissue 2D-page spot 71B, AOEB166, Antioxidant enzyme B166, Alu corepressor 1) Copy Product Info

Synonyms: TPx type VI, Thioredoxin reductase, Thioredoxin peroxidase PMP20, Prx-V, PRDX5, PLP, Peroxisomal antioxidant enzyme, Peroxiredoxin-5, Peroxiredoxin V, Liver tissue 2D-page spot 71B, AOEB166, Antioxidant enzyme B166, Alu corepressor 1

Catalog No. TMPJ-00933 Copy Product Info

Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.

Pack Size	Price	USA Stock	Global Stock
5 µg	$72	-	In Stock
10 µg	$116	-	In Stock
20 µg	$176	7-10 days	7-10 days
50 µg	$310	7-10 days	7-10 days
100 µg	$532	7-10 days	7-10 days
200 µg	$919	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.
Species	Human
Expression System	HEK293 Cells
Tag	N-6xHis
Accession Number	P30044
Amino Acid	Met53-Leu214
Construction	Met53-Leu214
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TPx type VI, Thioredoxin reductase, Thioredoxin peroxidase PMP20, Prx-V, PRDX5, PLP, Peroxisomal antioxidant enzyme, Peroxiredoxin-5, Peroxiredoxin V, Liver tissue 2D-page spot 71B, AOEB166, Antioxidant enzyme B166, Alu corepressor 1
Research Background	Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Peroxiredoxins is overexpressed in breast cancer tissues to a great extent suggesting that they has a proliferative effect and may be related to cancer development or progression. Peroxiredoxin 5 (PRDX5) is a thioredoxin peroxidase that belongs to the atypical 2-Cys class of the TSA/ahpC family of peroxiredoxins. PRDX5 is a widely expressed mitochondrial antioxidant enzyme that reduces hydrogen peroxide, alkyl hydroperoxides, and peroxynitrite. In human cells, this enzyme is present in the cytosol, mitochondria, peroxisomes, and nucleus.

Chemical Properties

Molecular Weight

17 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.