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Alogliptin

Name: Alogliptin
Brand: TargetMol
SKU: T6192
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T6192Cas No. 850649-61-5

Alias SYR-322

Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.

Alogliptin

🥰Excellent

Purity: 99.63%

Catalog No. T6192Alias SYR-322Cas No. 850649-61-5

Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$46	In Stock
10 mg	$61	In Stock
25 mg	$82	In Stock
50 mg	$98	In Stock
100 mg	$147	In Stock
200 mg	$218	In Stock
1 mL x 10 mM (in DMSO)	$51	In Stock

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Batch Information

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Purity:99.63%

Resource Download

COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.
Targets&IC50	DPP4:<10 nM
Synonyms	SYR-322

Chemical Properties

Molecular Weight	339.39
Formula	C₁₈H₂₁N₅O₂
Cas No.	850649-61-5
Smiles	Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2ccccc2C#N)c1=O
Relative Density.	1.342 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 68 mg/mL (200.36 mM), Sonication is recommended.

H2O: 2 mg/mL (5.89 mM), Sonication is recommended.

Ethanol: 60 mg/mL (176.79 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9465 mL	14.7323 mL	29.4646 mL	147.3231 mL
5 mM	0.5893 mL	2.9465 mL	5.8929 mL	29.4646 mL

Ethanol/DMSO

	1mg	5mg	10mg	50mg
10 mM	0.2946 mL	1.4732 mL	2.9465 mL	14.7323 mL
20 mM	0.1473 mL	0.7366 mL	1.4732 mL	7.3662 mL
50 mM	0.0589 mL	0.2946 mL	0.5893 mL	2.9465 mL
100 mM	0.0295 mL	0.1473 mL	0.2946 mL	1.4732 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc