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Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody
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Catalog No. TMAC-04124
Alias TrkA (p-Y791), TrkA (p-Tyr791), p-TrkA (Y791), p-TrkA (Tyr791)
Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr791). Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody can be used in IHC.
Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody
Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody
😃Good
Catalog No. TMAC-04124Alias TrkA (p-Y791), TrkA (p-Tyr791), p-TrkA (Y791), p-TrkA (Tyr791)
Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr791). Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TrkA (Tyr791). Anti-Phospho-TrkA (Tyr791) Polyclonal Antibody can be used in IHC. |
| Synonyms | TrkA (p-Y791), TrkA (p-Tyr791), p-TrkA (Y791), p-TrkA (Tyr791) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody TMAC-04124 (left) or the same antibody preincubated with blocking peptide (right).  |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 791 (P-V-Y(p)-L-D) derived from Human Trk A |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 140 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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