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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

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Catalog No. T39970Cas No. 2388520-36-1
Alias TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high tumor efficacy. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid, which can be cleaved.

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Other Forms of TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride:
TLR7/8 agonist 4 hydroxy-PEG10-acidT399682388520-17-8
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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

😃Good
Catalog No. T39970Alias TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochlorideCas No. 2388520-36-1
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high tumor efficacy. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid, which can be cleaved.
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Bioactivity
Description
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high tumor efficacy. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid, which can be cleaved.
In vitro
ADCs consist of an antibody conjugated to an ADC cytotoxin via an ADC linker.
SynonymsTLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Chemical Properties
Molecular Weight873.48
FormulaC41H69ClN6O12
Cas No.2388520-36-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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