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Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody (Synonyms: p-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH...)

Catalog No. TMAC-02247 Copy Product Info
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Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITCH (Tyr420). Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody can be used in IHC.

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-02247
Synonyms p-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH (p-Tyr420)

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITCH (Tyr420). Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody can be used in IHC.

Anti-Phospho-ITCH
(Tyr420) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITCH (Tyr420). Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody can be used in IHC.
Synonymsp-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH (p-Tyr420)
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human brain tissue using ITCH (Phospho-Tyr420) antibody TMAC-02247 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivity
Application
Recommended Dose
IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundAtrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 420(F-I-Y(p)-G-N) derived from Human ITCH
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 102 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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