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Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP (7L454)
(Synonyms: VH7183, Ighg1, Igh-4) Copy Product Info
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Synonyms: VH7183, Ighg1, Igh-4
Catalog No. TMAY-00001H Copy Product Info
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Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP (7L454) is a HRP-conjugated Rabbit antibody targeting IgG1. Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP (7L454) can be used in ELISA,IHC-P,WB.
Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP
(7L454)
(7L454)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μg | $180 | 7-10 days | 7-10 days | |
| 100 μg | $563 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP (7L454) is a HRP-conjugated Rabbit antibody targeting IgG1. Rabbit Anti-Mouse IgG1 Secondary Antibody-HRP (7L454) can be used in ELISA,IHC-P,WB. |
| Synonyms | VH7183, Ighg1, Igh-4 |
| Ig Type | Rabbit IgG |
| Clone | 7L454 |
| Reactivity | Mouse |
| Specificity | This antibody recognizes mouse IgG1, but no reacts to Mouse IgG2a, IgG2b, IgG3, IgM, Rabbit IgG, Human IgG. |
| Application | |
| Recommended Dose | WB: 0.1-1μg/mL; ELISA: 0.1-1 μg/mL; IHC-P: 0.3-2.5 μg/mL |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IgG1 (rM IgG1; 10690-MNAHP01868-1Val98-Lys324,C102S), and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (5 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Mouse IgG1-Fc Protein |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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