LTBR Protein, Human, Recombinant (hFc)

Name: LTBR Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-05039
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TNFRSF3, TNFR-RP, TNF-R-III, TNFR3, TNFR2-RP, TNFCR, lymphotoxin β receptor (TNFR superfamily, member 3), lymphotoxin beta receptor (TNFR superfamily, member 3), LT-β-R, LT-BETA-R, D12S370, CD18) Copy Product Info

Synonyms: TNFRSF3, TNFR-RP, TNF-R-III, TNFR3, TNFR2-RP, TNFCR, lymphotoxin β receptor (TNFR superfamily, member 3), lymphotoxin beta receptor (TNFR superfamily, member 3), LT-β-R, LT-BETA-R, D12S370, CD18

Catalog No. TMPY-05039 Copy Product Info

Purity: 95.9%

LTBR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P36941-1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$48	-	In Stock
10 µg	$75	-	In Stock
20 µg	$118	-	In Stock
50 µg	$229	-	In Stock
100 µg	$386	-	In Stock
200 µg	$660	7-10 days	7-10 days
500 µg	$1,330	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:95.9%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	LTBR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P36941-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P36941-1
Construction	A DNA sequence encoding the human LTBR (NP_002333.1) (Gln31-Met227) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 31
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	TNFRSF3, TNFR-RP, TNF-R-III, TNFR3, TNFR2-RP, TNFCR, lymphotoxin β receptor (TNFR superfamily, member 3), lymphotoxin beta receptor (TNFR superfamily, member 3), LT-β-R, LT-BETA-R, D12S370, CD18
Research Background	LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. The tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necrosis factors. The receptor cooperates with an adaptor protein (such as TRADD, TRAF, RIP), which is important in determining the outcome of the response. LTBR is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. LTBR specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphotoxin-beta). LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of this protein can trigger apoptosis. Not only does the LTBR help trigger apoptosis, but it can also lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. It is also essential for the development and organization of the secondary lymphoid organs and chemokine release.

Chemical Properties

Molecular Weight

47.8 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.