Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-TROP-2 Antibody (6N25) (Synonyms: tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M...)
Catalog No. TMAY-00815 Copy Product Info
🥰Excellent
Anti-TROP-2 Antibody (6N25) is a Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody (6N25) can be used in ELISA(Cap),ICC/IF,IHC-P.
Anti-TROP-2 Antibody (6N25)
Copy Product Info🥰Excellent
Catalog No. TMAY-00815
Synonyms tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1
Anti-TROP-2 Antibody (6N25) is a Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody (6N25) can be used in ELISA(Cap),ICC/IF,IHC-P.
Anti-TROP-2 Antibody
(6N25)
(6N25)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $70 | 7-10 days | 7-10 days | |
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TROP-2 Antibody (6N25) is a Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody (6N25) can be used in ELISA(Cap),ICC/IF,IHC-P. |
| Synonyms | tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1 |
| Ig Type | Mouse IgG1 |
| Clone | 6N25 |
| Reactivity | Human, Rhesus, Cynomolgus;
Not React with: Mouse, Rat |
| Specificity | Human, Rhesus, Cynomolgus Has cross-reactivity in ELISA with Human TROP2 / TACSTD2 Rhesus / Cynomolgus TROP2 No cross-reactivity in ELISA with Human BCAM / CD239 Human VCAM1 / CD106 Human ICAM1 / CD54 Human CD146 / MCAM / MUC18 Human CD171 / NCAML1 / L1CAM Human Cadherin-1 / E-cadherin / CDH1 / CD324 Mouse TROP2 / TACSTD2 Rat TROP-2 / TACSTD2 |
| Verified Activity | 1. Immunofluorescence staining of human TROP2 in MCF-7 cells with mouse monoclonal antibody (1:60). The image showing membrane staining of MCF-7 cells. 2. Immunochemical staining of human TROP2 in human rectal cancer with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human TROP2 in human placenta with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of cytotrophoblast. 4. Immunochemical staining of human TROP2 in human mammary gland with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of alveolus epithelium. 5. Immunofluorescence staining of TROP-2 in NCI-N87 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with mouse anti-Human TROP-2 monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cell membrane. |
| Application | |
| Recommended Dose | IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100; ELISA(Cap): 1:250-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TROP2 extracellular domain (rh TROP2; TMPY-01262; NP_002344.2; Met 1-Thr 274). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TROP2 protein (TMPY-01262) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-TROP-2 Antibody (6N25) | purchase Anti-TROP-2 Antibody (6N25) | Anti-TROP-2 Antibody (6N25) cost | order Anti-TROP-2 Antibody (6N25)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.