CRTAM Protein, Human, Recombinant (His)

Name: CRTAM Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01674
Rating: 4.5 (1 reviews)

(Synonyms: cytotoxic and regulatory T cell molecule, CD355) Copy Product Info

Synonyms: cytotoxic and regulatory T cell molecule, CD355

Catalog No. TMPY-01674 Copy Product Info

CRTAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is O95727.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$108	7-10 days	7-10 days
20 µg	$178	7-10 days	7-10 days
50 µg	$359	7-10 days	7-10 days
100 µg	$696	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human CRTAM, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CRTAM Antibody, hFc Tag with the EC50 of 57.3 ng/ml determined by ELISA.
Description	CRTAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.1 kDa and the accession number is O95727.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	O95727-1
Construction	Ser18-Gly287
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	cytotoxic and regulatory T cell molecule, CD355
Research Background	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Chemical Properties

Molecular Weight

31.1 kDa (Predicted); 55-70 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.