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Anti-Ctip2 Antibody (8M731) (Synonyms: ZNF856B, zinc finger protein hRit1 alpha, Rit1, Rit 1, Radiation-indu...)

Catalog No. TMAC-01013 Copy Product Info
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Anti-Ctip2 Antibody (8M731) is a Rabbit antibody targeting Ctip2. Anti-Ctip2 Antibody (8M731) can be used in FCM,ICC,IHC,WB.

Anti-Ctip2 Antibody (8M731)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01013
Synonyms ZNF856B, zinc finger protein hRit1 alpha, Rit1, Rit 1, Radiation-induced tumor suppressor gene 1 protein, Radiation induced tumor suppressor gene 1 protein, Radiation induced tumor suppressor gene 1, hRIT1 alpha, hRit1, CTIP-2, CTIP2, Ctip 2, COUP-TF-interacting protein 2, COUP-TF interacting protein 2, COUP TF interacting protein 2, BCL11B/TRDC fusion, BCL-11B, Bcl11b, B-cell lymphoma/leukemia 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B, BC11B_HUMAN, B cell lymphoma/leukemia 11B, B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein, ATL1-delta, ATL1 gamma, ATL1 beta, ATL1 alpha, ATL1

Anti-Ctip2 Antibody (8M731) is a Rabbit antibody targeting Ctip2. Anti-Ctip2 Antibody (8M731) can be used in FCM,ICC,IHC,WB.

Anti-Ctip2 Antibody
(8M731)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Ctip2 Antibody (8M731) is a Rabbit antibody targeting Ctip2. Anti-Ctip2 Antibody (8M731) can be used in FCM,ICC,IHC,WB.
SynonymsZNF856B, zinc finger protein hRit1 alpha, Rit1, Rit 1, Radiation-induced tumor suppressor gene 1 protein, Radiation induced tumor suppressor gene 1 protein, Radiation induced tumor suppressor gene 1, hRIT1 alpha, hRit1, CTIP-2, CTIP2, Ctip 2, COUP-TF-interacting protein 2, COUP-TF interacting protein 2, COUP TF interacting protein 2, BCL11B/TRDC fusion, BCL-11B, Bcl11b, B-cell lymphoma/leukemia 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B, BC11B_HUMAN, B cell lymphoma/leukemia 11B, B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein, ATL1-delta, ATL1 gamma, ATL1 beta, ATL1 alpha, ATL1
Ig Type
IgG
Clone
8M731
Reactivity
Human
Verified Activity
1. Western blot analysis of Ctip2 on THP-1 cells lysates using anti-Ctip2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Ctip2 antibody. Counter stained with hematoxylin.
3. ICC staining Ctip2 in LO2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Jurkat cells with Ctip2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundBcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 100/110 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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