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PPNDS

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Catalog No. T23180Cas No. 1021868-77-8

P2X1 receptor antagonist

PPNDS

PPNDS

😃Good
Catalog No. T23180Cas No. 1021868-77-8
P2X1 receptor antagonist
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$71335 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
P2X1 receptor antagonist
Targets&IC50
ADAM10:1.2 μM
Chemical Properties
Molecular Weight629.42
FormulaC18H15N4NaO14PS2
Cas No.1021868-77-8
Smiles[Na].O=CC1=C(O)C(=NC(N=NC=2C=C3C(C=C(C=C3S(=O)(=O)O)N(=O)=O)=C(C2)S(=O)(=O)O)=C1COP(=O)(O)O)C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mM, Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.5888 mL7.9438 mL15.8876 mL79.4382 mL
5 mM0.3178 mL1.5888 mL3.1775 mL15.8876 mL
10 mM0.1589 mL0.7944 mL1.5888 mL7.9438 mL
20 mM0.0794 mL0.3972 mL0.7944 mL3.9719 mL
50 mM0.0318 mL0.1589 mL0.3178 mL1.5888 mL
100 mM0.0159 mL0.0794 mL0.1589 mL0.7944 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PPNDS
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