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PPNDS

Name: PPNDS
Brand: TargetMol
SKU: T23180
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T23180Cas No. 1021868-77-8

P2X1 receptor antagonist

PPNDS

😃Good

Catalog No. T23180Cas No. 1021868-77-8

P2X1 receptor antagonist

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$713	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Product Introduction

Bioactivity

Description	P2X1 receptor antagonist
Targets&IC50	ADAM10:1.2 μM

Chemical Properties

Molecular Weight	629.42
Formula	C₁₈H₁₅N₄NaO₁₄PS₂
Cas No.	1021868-77-8
Smiles	[Na].O=CC1=C(O)C(=NC(N=NC=2C=C3C(C=C(C=C3S(=O)(=O)O)N(=O)=O)=C(C2)S(=O)(=O)O)=C1COP(=O)(O)O)C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mM, Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.5888 mL	7.9438 mL	15.8876 mL	79.4382 mL
5 mM	0.3178 mL	1.5888 mL	3.1775 mL	15.8876 mL
10 mM	0.1589 mL	0.7944 mL	1.5888 mL	7.9438 mL
20 mM	0.0794 mL	0.3972 mL	0.7944 mL	3.9719 mL
50 mM	0.0318 mL	0.1589 mL	0.3178 mL	1.5888 mL
100 mM	0.0159 mL	0.0794 mL	0.1589 mL	0.7944 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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PPNDS

PPNDS

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Product Introduction

Calculator

In Vivo Formulation Calculator (Clear solution)

Dose Conversion

Tech Support

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