Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 487.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 3,250.00 |
Description | Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
Species | Human |
Expression System | HEK293 |
Tag | C-mFc |
Accession Number | AAH17865 |
Synonyms | FCGR3, IGFR3, FcR-10, Fc γ RIIIA/CD16a (V176) Domain 2 Protein, IMD20, Fc γ RIIIA, FcRIIIa, FCGR3A, FcRIII, FcgRIIIA, CD16A, FCG3, CD16, FCGRIII, Fc gamma RIIIA |
Construction | Recombinant Human Fc gamma RIIIA/CD16a (V176) Domain 2 Protein is expressed from HEK293 with mFc tag at the C-terminus. It contains Gly107-Thr189.[Accession |AAH17865] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 35.29 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
Stability & Storage |
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) FCGR3 IGFR3 FcR-10 Fc γ RIIIA/CD16a (V176) Domain 2 Protein IMD20 Fc γ RIIIA FcRIIIa FCGR 3 FCGR3A FcRIII IGFR-3 IGFR 3 FcgRIIIA CD16A FCG3 FCGR-3 CD-16 FCG-3 CD 16 CD16 IMD 20 FCGRIII Fc gamma RIIIA FCG 3 IMD-20 recombinant recombinant-proteins proteins protein