Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.[2],[1] 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.[3],[4]
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 65.00 | |
5 mg | 35 days | $ 255.00 | |
10 mg | 35 days | $ 418.00 | |
25 mg | 35 days | $ 878.00 |
Description | 1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.[2],[1] 1-Oleoyl lysophosphatidic acid is the most potent of the LPA analogs for calcium mobilization in A431 cells and for growth stimulation of a variety of cell lines.[3],[4] |
Synonyms | Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA, 1-Oleoyl Lysophosphatidic Acid |
Molecular Weight | 436.526 |
Formula | C21H41O7P |
CAS No. | 65528-98-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 25 mg/mL
DMF: 2 mg/mL
DMSO: 2.5 mg/mL
PBS (pH 7.2): 3 mg/mL
You can also refer to dose conversion for different animals. More
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1-Oleoyl Lysophosphatidic Acid 65528-98-5 1 Oleoyl Lysophosphatidic Acid Oleoyl-sn-3-Glycerophosphate 1Oleoyl Lysophosphatidic Acid 1-Oleoyl LPA inhibitor inhibit