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1-Oleoyl Lysophosphatidic Acid
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Catalog No. T36907Cas No. 65528-98-5
Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
1-Oleoyl Lysophosphatidic Acid
Copy Product Info😃Good
Catalog No. T36907Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPACas No. 65528-98-5
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg (22.91 mM * 100 μL in Ethanol) | $94 | 35 days | 35 days | |
| 5 mg (22.91 mM * 500 μL in Ethanol) | $369 | 35 days | 35 days | |
| 10 mg (22.91 mM * 1 mL in Ethanol) | $593 | 35 days | 35 days | |
| 25 mg (22.91 mM * 2.5 mL in Ethanol) | $1,270 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Color:Transparent
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| Description | 1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis. |
| In vivo | METHODS: 1-Oleoyl Lysophosphatidic Acid(0.4-2 μg, i.v. for 9 weeks) treated rats and behaviorally assessed. RESULTS: 1-Oleoyl Lysophosphatidic Acid induced anxiety-like responses in the elevated plus maze (EPM). [5] |
| Synonyms | Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA |
| Molecular Weight | 436.52 |
| Formula | C21H41O7P |
| Cas No. | 65528-98-5 |
| Smiles | O(C(CCCCCCC/C=C\CCCCCCCC)=O)C[C@H](COP(=O)(O)O)O |
| Relative Density. | 1.103 g/cm3 (Predicted) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol: 10 mg/mL (22.91 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL (2.29 mM), Sonication is recommended. DMF: 1 mg/mL (2.29 mM), Sonication is recommended. DMSO: 1 mg/mL (2.29 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL (2.29 mM), Sonication is recommended. |
Solution Preparation Table | |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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