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1-Oleoyl Lysophosphatidic Acid
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Catalog No. T36907Cas No. 65528-98-5
Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
1-Oleoyl Lysophosphatidic Acid
😃Good
Catalog No. T36907Alias Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPACas No. 65528-98-5
1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg (22.91 mM * 100 μL in Ethanol) | $94 | 35 days | 35 days | |
| 5 mg (22.91 mM * 500 μL in Ethanol) | $369 | 35 days | 35 days | |
| 10 mg (22.91 mM * 1 mL in Ethanol) | $593 | 35 days | 35 days | |
| 25 mg (22.91 mM * 2.5 mL in Ethanol) | $1,270 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Concentration:10 mg/mL
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can exert multiple biological effects in various disease states of the kidney by activating a complex network of at least six homologous G protein-coupled receptors and their heterotrimeric G proteins. 1-Oleoyl Lysophosphatidic Acid promotes polarization of BV-2 and primary murine microglia toward an M1-like phenotype and can be used to study cancer and atherosclerosis. |
| In vivo | METHODS: 1-Oleoyl Lysophosphatidic Acid(0.4-2 μg, i.v. for 9 weeks) treated rats and behaviorally assessed. RESULTS: 1-Oleoyl Lysophosphatidic Acid induced anxiety-like responses in the elevated plus maze (EPM). [5] |
| Synonyms | Oleoyl-sn-3-Glycerophosphate, 1-Oleoyl LPA |
| Molecular Weight | 436.52 |
| Formula | C21H41O7P |
| Cas No. | 65528-98-5 |
| Smiles | O(C(CCCCCCC/C=C\CCCCCCCC)=O)C[C@H](COP(=O)(O)O)O |
| Relative Density. | 1.103 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol: 10 mg/mL (22.91 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL (2.29 mM), Sonication is recommended. DMF: 1 mg/mL (2.29 mM), Sonication is recommended. DMSO: 1 mg/mL (2.29 mM), Sonication is recommended. PBS (pH 7.2): 1 mg/mL（2.29 mM), Sonication is recommended. |
Solution Preparation Table | |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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